Iodoethane → HCID 12813189, compound

HRID 1154987Notes

Reaction equation

HRID 1154987 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[C:12](=[O:13])[N:11]([C:14]3[CH:15]=[C:16]([C:20]([F:23])([F:22])[F:21])[CH:17]=[CH:18][CH:19]=3)[NH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:30](I)[CH3:31]>C(O)C>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[C:12](=[O:13])[N:11]([C:14]3[CH:15]=[C:16]([C:20]([F:21])([F:22])[F:23])[CH:17]=[CH:18][CH:19]=3)[N:10]([CH2:30][CH3:31])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 1486556HCID 1486556, compound

Product 1

HCID 12813189HCID 12813189, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4.6 grams of the pyrazolinone prepared above, 4 grams potassium carbonate, 15 ml. ethyl iodide and 50 ml. ethanol was refluxed overnight. The reaction product mixture was worked up in the customary way to yield 1.8 grams of the desired product, m.p.=113°-114° C.

Sources & evidence

ORD record
ord-a9247ad3fc2e45f380947a0b8c2fa658
Source dataset
uspto-grants-1981_11
Patent number
US04299614

Reaction notes

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