Methanol → HCID 13470384, compound

HRID 1155526Notes

Reaction equation

HRID 1155526 reaction equation
[CH3:1][N:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]([F:15])([F:14])[F:13])[CH:10]=2)[C:5](=[O:16])[C:4]([S:17]([CH3:19])=[O:18])=[CH:3]1.CO.C(OCC)(=[O:24])C>ClCCl>[CH3:1][N:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]([F:13])([F:14])[F:15])[CH:10]=2)[C:5](=[O:16])[C:4]([S:17]([CH3:19])(=[O:24])=[O:18])=[CH:3]1

Participants

5

Reactant 3

HCID 887MethanolHCID 8857Ethyl AcetateHCID 13470356HCID 13470356, compound

Product 1

HCID 13470384HCID 13470384, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1-methyl-3-methylsulphinyl-7-trifluoromethyl-4-quinolone was oxidised in dichloromethane at 0° to give 1-methyl-3-methylsulphonyl-7-trifluoromethyl-4-quinolone, m.p. 300°-301° (from methanol:ethyl acetate)

Sources & evidence

ORD record
ord-078ce9165c804e959b6d9a2315f94caf
Source dataset
uspto-grants-1981_11
Patent number
US04302460

Reaction notes

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