反应详情

温度

20 °C

17.8 g (0.25 mol) of chlorine were passed into a solution of 42.6 g (0.2 mol) of 3-carboxy-3-cyano-2,2-dimethyl-propane-1-carboxylic acid ethyl ester and 41 g of sodium acetate in 400 ml of water at 20° C. The mixture was subsequently stirred at 20° C. for 5 hours and then acidified with dilute HCl. The acid solution was worked up as described under Example 1. 28 g (69% of theory) of 3-chloro-3-cyano-2,2-dimethyl-propane-1-carboxylic acid ethyl ester were obtained in the form of a colorless oil of boiling point 80°-82° C./1 mm Hg.