反应详情

A mixture containing 5 g of methyl 2-[[(4-methylquinazolin-2-yl)aminocarbonyl]aminosulfonyl]benzoate, 20 ml of ethanol, 2.5 ml of water and 2.5 g of potassium hydroxide is stirred at ambient temperature and pressure for 18 hours. The mixture is then diluted with water and 20 ml of concentrted hydrochloric acid added with stirring. The resulting precipitate is filtered, washed with water and dried.

1. additionadded
2. stirringwith stirring
3. filtrationThe resulting precipitate is filtered
4. washwashed with water
5. customdried