Phenylacetic Acid → Benzeneacetic acid, (4-methoxyphenyl)methyl ester

HRID 1156154Notes

Reaction equation

HRID 1156154 reaction equation
[C:1]1([CH2:7][C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Na].[CH3:12][O:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18]Br)=[CH:16][CH:15]=1>>[C:1]1([CH2:7][C:8]([O:10][CH2:18][C:17]2[CH:20]=[CH:21][C:14]([O:13][CH3:12])=[CH:15][CH:16]=2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 999Phenylacetic AcidHCID 1650214-Methoxybenzyl bromideHCID 5360545Sodium

Product 1

HCID 7599Benzeneacetic acid, (4-methoxyphenyl)methyl ester

Procedure

Phenylacetic acid, sodium salt, is reacted with 4-methoxybenzyl bromide to obtain 4-methoxybenzyl phenylacetate;

Sources & evidence

ORD record
ord-e972c987720044458bc3b60e68310695
Source dataset
uspto-grants-1982_06
Patent number
US04334079

Reaction notes

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