反应详情

Thirty-five grams (82 mmoles) of 2-chloro-1-(p-chlorophenylsulfonyl)ethyl p-bromophenyl sulfide was dissolved in 100 ml of tetrahydrofuran and treated with 12 ml (86 mmoles) of triethylamine. The mixture was diluted with 100 ml of diethyl ether and allowed to stand for 15 minutes. The precipitated triethylamine hydrochloride was separated by filtration. Evaporation of solvent from the filtrate gave 35 g of crude solid m.p. 45°-95°. Recrystallization from 100 ml of ethyl acetate-pentane (45:55) gave 13 g of pure product, m.p. 97°-99°.

1. customThe precipitated triethylamine hydrochloride was separated by filtration
2. customEvaporation of solvent from the filtrate
3. customgave 35 g of crude solid m.p. 45°-95°
4. customRecrystallization from 100 ml of ethyl acetate-pentane (45:55)