Hydrogen Bromide → HCID 13023242, compound

HRID 1156994Notes

Reaction equation

HRID 1156994 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]([C:9]23[CH2:17][CH2:16][CH2:15][CH:14]2[CH2:13][N:12]([CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH2:11][CH2:10]3)[CH:6]=[CH:7][CH:8]=1.Br>C(O)(=O)C>[OH:2][C:3]1[CH:4]=[C:5]([C:9]23[CH2:17][CH2:16][CH2:15][CH:14]2[CH2:13][N:12]([CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH2:11][CH2:10]3)[CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 13023240HCID 13023240, compound

Product 1

HCID 13023242HCID 13023242, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Following the procedure set forth in Example 40, 4a-(3-methoxyphenyl)-2-n-pentyl-2,3,4,4a,5,6,7,7a-octahydro-1H-2-pyrindine was reacted with aqueous hydrobromic acid in glacial acetic acid to afford 4a-(3-hydroxyphenyl)-2-n-pentyl-2,3,4,4a,5,6,7,7a-octahydro-1H-2-pyrindine, which was then converted to the corresponding hydrogen bromide salt. M.P. 171°-173° C.

Sources & evidence

ORD record
ord-31fe6e4ac20541869e351123b95b284c
Source dataset
uspto-grants-1982_06
Patent number
US04337341

Reaction notes

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