Potassium Carbonate → HCID 11716760, compound

HRID 1157693Notes

Reaction equation

HRID 1157693 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:16]1([CH2:22][CH2:23][CH2:24]Br)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.C([O-])([O-])=O.[K+].[K+]>C(#N)C>[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH:13]([CH2:24][CH2:23][CH2:22][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 12503(3-Bromopropyl)benzeneHCID 111717071-(3-Phenylpropyl)piperidine

Product 1

HCID 11716760HCID 11716760, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

3-Phenylpropylpiperidine (1 eq) was reacted with 3-phenylbromopropane (1 eq) in the presence of K2CO3 in refluxing acetonitrile over night. The product obtained was worked up and purified on a column of silica. The 500 MHz 1H NMR is in accordance with the expected structure.

Workup

  1. customThe product obtained
  2. custompurified on a column of silica

Sources & evidence

ORD record
ord-8f304fe96b774fa197bc0a26ddefe6a3
Source dataset
uspto-grants-2010_10
Patent number
US07807695B2

Reaction notes

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