Acetic Acid → Methyl 4-(2-acetylhydrazino)benzoate

HRID 1159640Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1159640
[NH:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1)[NH2:2].[CH3:13][C:14](O)=[O:15]>C([O-])(=O)C.[Na+]>[C:14]([NH:2][NH:1][C:3]1[CH:4]=[CH:5][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:11][CH:12]=1)(=[O:15])[CH3:13]

Komponenten

4

Edukt 2

HCID 176Acetic AcidHCID 408928Methyl 4-hydrazinylbenzoate

Produkt 1

HCID 12765612Methyl 4-(2-acetylhydrazino)benzoateAusbeute 115,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 517045Sodium AcetateLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

5.5 g of methyl 4-hydrazinobenzoate are dissolved in 38.2 ml of AcOH containing 2.4 g of sodium acetate and the solution is heated at 80° C. for 18 hours. The inorganic material is removed by suction filtration and then evaporation is carried out and the residue is taken up in a minimum of Et2O. Suction filtration gives 7.97 g of the expected compound.

Aufarbeitung

  1. customThe inorganic material is removed by suction filtration
  2. customevaporation
  3. filtrationSuction filtration

Quellen und Nachweise

ORD-Eintrag
ord-f68e4994441549d09f98154a8133fa76
Quelldatensatz
uspto-grants-2010_10
Patentnummer
US07812165B2

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