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HRID1161921

反应详情

EQUATION

反应方程式

HRID 1161921 的结构方程式

REACTANTS

反应物

3
反应SMILES：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

反应SMILES：O=C(OC(=O)C(F)(F)F)C(F)(F)F
HCID9845

Trifluoroacetic anhydride

C4F6O3

反应SMILES：NC(=O)[C@@H]1C[C@H](F)CN1C(=O)OCc1ccccc1
HCID58136204

未命名化合物

PRODUCTS

产物

1
反应SMILES：N#C[C@@H]1C[C@H](F)CN1C(=O)OCc1ccccc1
HCID23626152

Benzyl (2S,4S)-2-cyano-4-fluoropyrrolidine-1-carboxylate

C13H13FN2O2

AUXILIARIES

试剂、催化剂与溶剂

1
反应SMILES：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Benzyl-(2S,4S)-2-aminocarbonyl-4-fluoropyrrolidine-1-carboxylate in dichloromethane was treated at 0° C. with Et3N (2.1 eq.) and trifluoroacetic anhydride was added dropwise.

WORKUP

后处理

  1. additionwas added dropwise