Tetrahydrofuran → HCID 13093543, compound

HRID 1163955Notes

Reaction equation

HRID 1163955 reaction equation
C(N(CC)CC)C.Cl.[CH2:9]([O:16][C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18]=1[CH:27]([OH:33])[C:28](=[NH:32])[O:29]CC)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[O:34]1CCC[CH2:35]1>C1(C)C=CC=CC=1>[CH2:9]([O:16][C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18]=1[CH:27]1[O:33][C:35](=[O:34])[NH:29][C:28]1=[O:32])[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

5

Reactant 3

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 20459888HCID 20459888, compound

Product 1

HCID 13093543HCID 13093543, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

By the procedure of Example 27, except that 2.1 equivalents rather than 3.2 equivalents of triethylamine were employed, ethyl 1-(2-benzyloxy-1-naphthyl)-1-hydroxymethanecarboximidate hydrochloride (4.0 g., 0.011 mole) in 180 ml. of tetrahydrofuran was converted to toluene recrystallized 5-(2-benzyloxy-1-naphthyl)-oxazolidine-2,4-dione (1.61 g., m.p. 197°-199.5° C.).

Workup

  1. customrecrystallized 5-(2-benzyloxy-1-naphthyl)-oxazolidine-2,4-dione (1.61 g., m.p. 197°-199.5° C.)

Sources & evidence

ORD record
ord-80e84b7677d545349f743e2f737233c6
Source dataset
uspto-grants-1983_01
Patent number
US04367234

Reaction notes

Loading…