N-bromobutanimide → HCID 20513484, compound

HRID 1164041Notes

Reaction equation

HRID 1164041 reaction equation
[CH3:1][O:2][C:3]1[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:4]=1[O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[F:17].[Br:18]N1C(=O)CCC1=O>C1C=CC=CC=1.N(C(C)(C)C#N)=NC(C)(C)C#N>[CH3:1][O:2][C:3]1[C:8]([CH2:9][Br:18])=[CH:7][CH:6]=[CH:5][C:4]=1[O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[F:17]

Participants

5

Reactant 2

HCID 67184N-bromobutanimideHCID 20513512HCID 20513512, compound

Product 1

HCID 20513484HCID 20513484, compoundYield 114.2%

Reagents, catalysts & solvents 2

HCID 6547AzobisisobutyronitrileCatalystHCID 241BenzeneSolvent

Procedure

A mixture of 2-fluorophenyl 2-methoxy-3-methylphenyl ether (11.5 g), N-bromosuccinimide (9 g) and azobisisobutyronitrile (0.9 g) in benzene (100 ml) was treated in a similar manner to that of Example 5-(3) to give oily 2-fluorophenyl 2-methoxy-3-bromomethylphenyl ether (17.6 g).

Workup

  1. additionwas treated in a similar manner to that of Example 5-(3)

Sources & evidence

ORD record
ord-3047d4ad969244f0b1eb63782bedf5bf
Source dataset
uspto-grants-1983_01
Patent number
US04367238

Reaction notes

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