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HRID1164112

反应详情

EQUATION

反应方程式

HRID 1164112 的结构方程式

REACTANTS

反应物

3
结构：CI
HCID6328

Methyl iodide

CH3I

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CCOC(=O)C(C#N)c1cccc(Sc2ccccc2C)c1OC
HCID20513407

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)C(C)(C#N)c1cccc(Sc2ccccc2C)c1OC
HCID20513434

未命名化合物

收率 102.2%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Sodium hydride (65%, 1.05 g), ethyl 2-cyano-2-[2-methoxy-3-(o-tolylthio)phenyl]acetate (9.4 g), methyl iodide (7.85 g) and dimethylformamide (40 ml) were treated in a similar manner to that of Example 22-(2) to give oily ethyl 2-cyano-2-[2-methoxy-3-(o-tolylthio)phenyl]propionate (10.0 g).