反应详情

32 g of 2-[2'-(2-methoxyethoxy)nitrobenzenesulfonamido]-4-hexadecyloxy-5-methylphenol was added to 300 ml of isopropyl alcohol together with 24 g of iron dust, 12 g of tri-iron tetroxide, 0.6 g of ammonium chloride, and 25 ml of water, and refluxed for 1 hour on a steam bath under stirring. After completion of the stirring, the mixture was hot-filtered and, after cooling the mother liquor, crystals thus formed were collected by filtration, washed with 50 ml of isopropyl alcohol, and air-dried. Yield: 23 g; m.p. 142° to 144° C.

1. temperaturerefluxed for 1 hour on a steam bath
2. filtrationAfter completion of the stirring, the mixture was hot-filtered
3. temperatureafter cooling the mother liquor, crystals
4. customthus formed
5. filtrationwere collected by filtration
6. washwashed with 50 ml of isopropyl alcohol
7. customair-dried