反应详情

In 150 ml of DMSO were dissolved 15.0 g of 2,3,5,6-tetramethylphenol and 28 ml of methyl iodide. Under ice-cooling 6.3 g of 60% sodium hydride in oil was added, and the mixture was stirred at room temperature for 1 hour. The excess sodium hydride was decomposed with MeOH and after addition of water extraction with ether was carried out. The extract was dried over sodium sulfate. Removal of the solvent by distillation leaves crystals which were recrystallized from MeOH.

1. additionwas added
2. dry with materialThe extract was dried over sodium sulfate
3. customRemoval of the solvent
4. distillationby distillation
5. customleaves crystals which
6. customwere recrystallized from MeOH