Methanesulfonic anhydride → HCID 20511946, compound

HRID 1164340Notes

Reaction equation

HRID 1164340 reaction equation
CS(OS(C)(=O)=O)(=O)=O.C1(C)[C:11]([S:16]([O:19][C:20]2[CH2:26][CH:25]3[N:22]([C:23](=[O:27])[CH2:24]3)[C:21]=2[C:28]([O:30][CH2:31][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)=[O:29])(=[O:18])=[O:17])=CC=CC=1>>[CH3:11][S:16]([O:19][C:20]1[CH2:26][CH:25]2[N:22]([C:23](=[O:27])[CH2:24]2)[C:21]=1[C:28]([O:30][CH2:31][C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)=[O:29])(=[O:17])=[O:18]

Participants

3

Reactant 2

HCID 81560Methanesulfonic anhydrideHCID 131712683Benzyl 3-toluenesulfonyloxy-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate

Product 1

HCID 20511946HCID 20511946, compound

Procedure

By substituting an equivalent amount of methanesulfonic anhydride for p-toluenesulfonic anhydride of Example 18, benzyl 3-methanesulfonyloxy-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate is obtained. Hydrogenolysis of this material by the method described in Example 19 affords sodium 3-methanesulfonyloxy-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate.

Sources & evidence

ORD record
ord-739406159dc347efafbb5391d299bf73
Source dataset
uspto-grants-1983_01
Patent number
US04369187

Reaction notes

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