Hydrochloric Acid → 4-[7-(3-Methanesulfonylamino-propoxy)-quinazolin-4-yl]-piperidine-1-carboxylic acid (4-morpholin-4-yl-phenyl)-amide
Reaction equation
[Al:40].[C:1]([O:2][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:24][CH2:25][CH2:26][CH2:27][NH:28][S:29](=[O:30])(=[O:31])[CH3:32])[cH:21][cH:22][c:23]23)[CH2:12][CH2:13]1)([CH3:3])([CH3:4])[CH3:5].[ClH:41].[F:33][C:34]([F:35])([F:36])[C:37]([OH:38])=[O:39].[N+:42]([c:43]1[cH:44][cH:45][c:46]([O:47][C:48](=[O:49])[NH:53][c:54]2[cH:55][cH:56][c:57]([N:60]3[CH2:61][CH2:62][O:63][CH2:64][CH2:65]3)[cH:58][cH:59]2)[cH:50][cH:51]1)([O-:52])=[O:66]>>[C:6](=[O:7])([N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:24][CH2:25][CH2:26][CH2:27][NH:28][S:29](=[O:30])(=[O:31])[CH3:32])[cH:21][cH:22][c:23]23)[CH2:12][CH2:13]1)[NH:53][c:54]1[cH:55][cH:56][c:57]([N:60]2[CH2:61][CH2:62][O:63][CH2:64][CH2:65]2)[cH:58][cH:59]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-892cdb16b176450fb3ee8c21bdc697d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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