m-Chloroperbenzoic acid → HCID 19757849, compound

HRID 1164870Notes

Reaction equation

HRID 1164870 reaction equation
[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].ClC1C=CC=C(C(OO)=[O:23])C=1>C(Cl)Cl>[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[N+:11]([O-:23])[CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 10867660Diethyl pyridin-3-ylphosphonate

Product 1

HCID 19757849HCID 19757849, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 1.5 g of 3-diethylphosphonopyridine, Bull. Chem. Soc. Jap. 55, 909 (1982), in 20 ml of methylene chloride is treated with 2.33 g m-chloroperbenzoic acid at room temperature. The reaction mixture is allowed to stir at room temperature overnight, then concentrated under vacuum. The residue is partitioned between ether and water, the aqueous layer is concentrated under vacuum to afford 3-(diethylphosphono)-pyridine-N-oxide as a yellow oil.

Workup

  1. concentrationconcentrated under vacuum
  2. customThe residue is partitioned between ether and water
  3. concentrationthe aqueous layer is concentrated under vacuum

Sources & evidence

ORD record
ord-fef240fb309c4c0fb2ba15c4b0325317
Source dataset
uspto-grants-1990_03
Patent number
US04906621

Reaction notes

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