Allylamine → HCID 22164314, compound

HRID 1164911Notes

Reaction equation

HRID 1164911 reaction equation
[Cl:1][C:2]1([S:8](Cl)(=[O:10])=[O:9])[NH:6][C:5]([Cl:7])=[CH:4][S:3]1.[CH2:12]([NH2:15])[CH:13]=[CH2:14]>>[CH2:12]([NH:15][S:8]([C:2]1([Cl:1])[NH:6][C:5]([Cl:7])=[CH:4][S:3]1)(=[O:10])=[O:9])[CH:13]=[CH2:14]

Participants

3

Reactant 2

HCID 7853AllylamineHCID 22164315HCID 22164315, compound

Product 1

HCID 22164314HCID 22164314, compound

Procedure

In analogy to Example 2, the N-allyl-2,4-dichlorothiazole-sulphonamide was prepared by reacting 2,4-dichlorothiazolesulphonyl chloride from Example 1 with anhydrous allylamine. Following recrystallization from petroleum ether/acetone (6:1), 7.6 g of product were obtained (28% of the theoretical yield), m.p.: 80°-81° C.

Workup

  1. customrecrystallization from petroleum ether/acetone (6:1)

Sources & evidence

ORD record
ord-dc4b9eb21bed44bf8803e6c2cca2fe9c
Source dataset
uspto-grants-1990_03
Patent number
US04906650

Reaction notes

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