反应详情

0.5 g of the product from Example 1 and 0.42 g of piperazine are boiled in 8 ml of dioxane for 3 hours. The mixture is then concentrated in vacuo and 8 ml of water are added to the residue. The solution formed is rendered neutral with HCl and the solid which has precipitated out isolated, washed and dried.

1. concentrationThe mixture is then concentrated in vacuo and 8 ml of water
2. additionare added to the residue
3. customThe solution formed
4. customthe solid which has precipitated out
5. customisolated
6. washwashed
7. customdried