Diethyl Carbonate → HCID 14745588, compound

HRID 1165399Notes

Reaction equation

HRID 1165399 reaction equation
[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:22](=O)([O:26]CC)[O:23][CH2:24][CH3:25].[O-]CC.[Na+]>C(O)C>[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]([C:22]([O:23][CH2:24][CH3:25])=[O:26])[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 3

HCID 7766Diethyl CarbonateHCID 2723922Sodium ethoxideHCID 14745587HCID 14745587, compound

Product 1

HCID 14745588HCID 14745588, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

The obtained ethyl 4-n-octyloxyphenylacetate (79 g), ethanol (14 ml), diethyl carbonate (300 ml) and sodium ethoxide (19.3 g) are mixed, and the mixture is heated with stirring while ethanol is distilling off. The reaction mixture is transferred into ice water and is acidified with hydrochloric acid. The organic layer is separated and the solvent is distilled off to give diethyl 4-n-octyloxyphenylmalonate (91.6 g).

Workup

  1. temperaturethe mixture is heated
  2. distillationis distilling off
  3. customThe organic layer is separated
  4. distillationthe solvent is distilled off

Sources & evidence

ORD record
ord-05edc2bd0a6f42ba8cc7319e0de07f33
Source dataset
uspto-grants-1990_03
Patent number
US04909957

Reaction notes

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