Hydrogen chloride-ethyl acetate → HCID 68920400, compound

HRID 1166194Notes

Reaction equation

HRID 1166194 reaction equation
[O:1]([CH2:5][C:6]1[N:11]=[C:10]([CH3:12])[C:9]([O:13][C:14](=[O:25])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:21][C:22](=[O:24])[CH3:23])=[CH:8][CH:7]=1)[N+:2]([O-:4])=[O:3].C(OCC)(=O)C.[ClH:32]>C(OCC)(=O)C>[ClH:32].[O:1]([CH2:5][C:6]1[N:11]=[C:10]([CH3:12])[C:9]([O:13][C:14](=[O:25])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:21][C:22](=[O:24])[CH3:23])=[CH:8][CH:7]=1)[N+:2]([O-:4])=[O:3]

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 68920401HCID 68920401, compound

Product 1

HCID 68920400HCID 68920400, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To a solution of 2-acetyloxybenzoic acid 6-(nitroxymethyl)-2-methylpyridinyl ester (1 g, 2.88 mmoles) in ethyl acetate (20 ml) cooled at 0° C., a solution of ethyl acetate/HCl 5M is added by dropping under stirring. It is left for one hour at 0° C., then the temperature is let reach room values. The formed precipitate is filtered and washed with ethyl ether. 900 mg of solid product are obtained.

Workup

  1. filtrationThe formed precipitate is filtered
  2. washwashed with ethyl ether

Sources & evidence

ORD record
ord-336e4822f95748449d61ed0e893c453c
Source dataset
uspto-grants-2003_09
Patent number
US06613784B1

Reaction notes

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