Oxalyl chloride → [1,1'-Biphenyl]-2-carbonyl chloride

HRID 1167105Notes

Reaction equation

HRID 1167105 reaction equation
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[C:7]1([C:16]2C=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:8](C(O)=O)=[CH:9][CH:10]=[CH:11][CH:12]=1>ClCCl.CN(C)C=O>[C:16]1([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:1]([C:2]([Cl:4])=[O:3])=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

5

Reactant 2

HCID 65578Oxalyl chlorideHCID 70357o-Phenylbenzoic acid

Product 1

HCID 12563768[1,1'-Biphenyl]-2-carbonyl chloride

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideSolventHCID 6344DichloromethaneSolvent

Procedure

1.54 ml (0.018 mol) of oxalyl chloride are added dropwise to a suspension of 3 g (0.015 mol)) of biphenyl-2-carboxylic acid in 100 ml of dichloromethane and 0.3 ml dimethylformamide at 0° C. After the reaction has ended the reaction mixture is concentrated by distillation and the biphenyl-2-carboxylic acid chloride is further reacted as a crude product.

Workup

  1. concentrationis concentrated by distillation
  2. customthe biphenyl-2-carboxylic acid chloride is further reacted as a crude product

Sources & evidence

ORD record
ord-3660cd3dbb764529b3dced22a5e6a9a5
Source dataset
uspto-grants-2003_09
Patent number
US06617325B1

Reaction notes

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