反应详情

To a solution of sesamol (10.0 g, 0.072 mol) in DMF (50 ml) was added sodium hydride (2.08 g, 0.087 mol) at rt under argon. After stirring for 1 h the mixture was treated with Iodomethane (13.5 ml, 0.216 mol) and stirred for another 18 h. Upon the removal of the solvent the residue was extracted with ethyl acetate and washed with water, dried (Na2SO4) and concentrated to afford the title compound as a dark brown oil (10.5 g, 96%).

1. stirringstirred for another 18 h
2. customUpon the removal of the solvent the residue
3. extractionwas extracted with ethyl acetate
4. washwashed with water
5. dry with materialdried (Na2SO4)
6. concentrationconcentrated