(4-Methoxyphenyl)boronic acid → HCID 22994375, compound

HRID 1167850Notes

Reaction equation

HRID 1167850 reaction equation
Br[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[CH3:10].[CH3:11][O:12][C:13]1[CH:18]=[CH:17][C:16](B(O)O)=[CH:15][CH:14]=1>>[CH3:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([C:2]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=2[CH3:10])=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 27374944-Bromo-3-methylbenzonitrile

Product 1

HCID 22994375HCID 22994375, compoundYield 80%

Procedure

4-Bromo-3-methylbenzonitrile and 4-methoxyphenylboronic acid were processed as described in Example 164A to provide the title compound (80% yield). 1HNMR (300 MHz, CDCl3) δ2.40 (3H), 3.73 (s, 3H), 6.84-7.60 (m, 7H); MS (DCI) m/z 224 (M+H)+.

Sources & evidence

ORD record
ord-8d3f6c2389db4461914abfb9190f3ac3
Source dataset
uspto-grants-2003_09
Patent number
US06620839B2

Reaction notes

Loading…