Tetrahydrofuran → 2-[(5-Fluoro-2-{[4-(hydroxymethyl)phenyl]amino}-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide
Reaction equation
[Al+3:34].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[F:1][c:2]1[c:3]([NH:20][c:21]2[c:22]([C:27](=[O:28])[NH:29][CH:30]([CH3:31])[CH3:32])[cH:23][cH:24][cH:25][cH:26]2)[n:4][c:5]([NH:8][c:9]2[cH:10][cH:11][c:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:18][cH:19]2)[n:6][cH:7]1.[H-:33].[H-:36].[H-:37].[H-:38].[Li+:35]>>[F:1][c:2]1[c:3]([NH:20][c:21]2[c:22]([C:27](=[O:28])[NH:29][CH:30]([CH3:31])[CH3:32])[cH:23][cH:24][cH:25][cH:26]2)[n:4][c:5]([NH:8][c:9]2[cH:10][cH:11][c:12]([CH2:13][OH:14])[cH:18][cH:19]2)[n:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-db455361f2b14b50b59a4a4a50c4cf20
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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