HRID1168520
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
产物
CONDITIONS
反应条件
- 温度
- 110 °C
PROCEDURE
实验过程
A mixture of 2-(hydroxymethyl)-4-methylaniline (10.0 g) and diethyl ethoxymethylenemalonate (18.5 g) is heated at 110° C. for 1 h. Crystallization from ether/hexane afforded 19.5 g of the title compound. Physical characteristics: M.p. 92-95° C.; Anal. Found: C, 62.49; H, 6.88; N, 4.60.
WORKUP
后处理
- customCrystallization from ether/hexane