(Phenylmethoxy)acetaldehyde → 2-(Benzyloxy) ethanol

HRID 1168612Notes

Reaction equation

HRID 1168612 reaction equation
C(=O)([O-])O.[Na+].[CH2:6]([O:13][CH2:14][CH:15]=[O:16])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[CH2:6]([O:13][CH2:14][CH:15]=[O:16])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[CH2:6]([O:13][CH2:14][CH2:15][OH:16])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 108989(Phenylmethoxy)acetaldehydeHCID 516892Sodium Bicarbonate

Product 2

HCID 121412-(Benzyloxy) ethanolHCID 108989(Phenylmethoxy)acetaldehyde

Procedure

Example 1 was repeated except that 2.5 g (30 mmoles) of sodium hydrogen carbonate was used instead of 2.6 g (15 mmoles ) of dipotassium hydrogen phosphate, to obtain 7.1 g of benzyloxyacetaldehyde and 4.5 g of 2-benzyloxyethanol (yield of benzyloxyacetaldehyde based on the 2-benzyloxyethanol that had reacted: 66.8%, ratio of recovery of 2-benzyloxyethanol: 29.6%).

Sources & evidence

ORD record
ord-016bf7d79d9742119113d1bb520a0dce
Source dataset
uspto-grants-2003_09
Patent number
US06624331B1

Reaction notes

Loading…