Dimethylformamide → {6-[3-(3-Chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridin-3-yl}-(1,1-dioxo-1lambda6-thiomorpholin-4-yl)-methanone

HRID 116969Notes

Reaction equation

HRID 116969 reaction equation
[CH:47]([N:48]([CH2:49][CH3:50])[CH:51]([CH3:52])[CH3:53])([CH3:54])[CH3:55].[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][o:10][c:11]([CH3:24])[c:12]2[CH2:13][O:14][c:15]2[n:16][cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23]2)[cH:5][cH:6][cH:7]1.[F:25][B-:26]([F:27])([F:28])[F:29].[O:64]=[CH:65][N:66]([CH3:67])[CH3:68].[S:56]1(=[O:62])(=[O:63])[CH2:57][CH2:58][NH:59][CH2:60][CH2:61]1.[n:30]1([O:31][C:32]([N:33]([CH3:34])[CH3:35])=[N+:36]([CH3:37])[CH3:38])[c:39]2[cH:40][cH:41][cH:42][cH:43][c:44]2[n:45][n:46]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][o:10][c:11]([CH3:24])[c:12]2[CH2:13][O:14][c:15]2[n:16][cH:17][c:18]([C:19](=[O:21])[N:59]3[CH2:58][CH2:57][S:56](=[O:62])(=[O:63])[CH2:61][CH2:60]3)[cH:22][cH:23]2)[cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 26255TetrafluoroborateHCID 81531DiisopropylethylamineHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 6484228Thiomorpholine 1,1-dioxideHCID 684448596-[3-(3-Chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid

Product 1

HCID 68934376{6-[3-(3-Chloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridin-3-yl}-(1,1-dioxo-1lambda6-thiomorpholin-4-yl)-methanone

Sources & evidence

ORD record
ord-8c7383d9176e4156ac353cc85e53fbbd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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