Oxalyl chloride → HCID 86054527, compound

HRID 1171444Notes

Reaction equation

HRID 1171444 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][OH:9])=[C:4]([O:10][CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:3]=1.C(Cl)(=O)C(Cl)=O>CS(C)=O>[I:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[O:9])=[C:4]([O:10][CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:3]=1

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 68767917HCID 68767917, compound

Product 1

HCID 86054527HCID 86054527, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

The procedure is the same as that described above, using 6.6 g, that is 18.8 mmol, of (4-iodo-2-phenethyloxyphenyl)methanol, 1.8 ml of oxalyl chloride and 3 ml of DMSO. After evaporation of the solvents, 6.4 g (96%) of the expected compound are recovered in the form of a yellow solid.

Workup

  1. customAfter evaporation of the solvents, 6.4 g (96%) of the expected compound
  2. customare recovered in the form of a yellow solid

Sources & evidence

ORD record
ord-764bdffd3f2c4c83ba26638ec00df4d7
Source dataset
uspto-grants-2010_11
Patent number
US07829588B2

Reaction notes

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