Hexane → HCID 57562627, compound

HRID 1172427Notes

Reaction equation

HRID 1172427 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]([O:10][CH3:11])=[O:9])[CH:5]=[C:4]([Br:12])[CH:3]=1.[C:13]([N:21]=[C:22]=[S:23])(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CCCCCC>O1CCCC1>[C:13]([NH:21][C:22](=[S:23])[NH:1][C:2]1[N:7]=[C:6]([C:8]([O:10][CH3:11])=[O:9])[CH:5]=[C:4]([Br:12])[CH:3]=1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

5

Reactant 3

HCID 8058HexaneHCID 68284Benzoyl isothiocyanateHCID 29919299Methyl 6-amino-4-bromopyridine-2-carboxylate

Product 1

HCID 57562627HCID 57562627, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

2.74 g of methyl 6-amino-4-bromopyridine-2-carboxylate was dissolved in 15 ml of tetrahydrofuran and 1.63 ml of benzoyl isothiocyanate was added thereto, followed by stirring at room temperature for 13 hours. To the reaction mixture was added 40 ml of hexane. The resulting solid was filtered and washed with hexane. The obtained solid was dried in vacuo to give the title compound.

Workup

  1. filtrationThe resulting solid was filtered
  2. washwashed with hexane
  3. customThe obtained solid was dried in vacuo

Sources & evidence

ORD record
ord-3ed8026681ef4d92b94a658b2e7ad497
Source dataset
uspto-grants-2010_11
Patent number
US07834018B2

Reaction notes

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