Hydrochloric Acid → HCID 22674054, compound

HRID 1173134Notes

Reaction equation

HRID 1173134 reaction equation
C([NH:8][CH:9]([CH3:23])[CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([NH:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH:12]=1)(OC(C)(C)C)=O.[ClH:24]>C(O)C>[ClH:24].[CH2:21]([O:20][C:18]([NH:17][C:13]1[CH:12]=[C:11]([CH2:10][CH:9]([NH2:8])[CH3:23])[CH:16]=[CH:15][CH:14]=1)=[O:19])[CH3:22]

Participants

4

Reactant 2

HCID 313Hydrochloric Acid2×HCID 22674117HCID 22674117, compound

Product 1

HCID 22674054HCID 22674054, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

N-Boc-1-methyl-2-(3-ethoxycarbonylaminophenyl)ethylamine (1.173 g, crude) was dissolved in ethanol (5.0 ml), to which was then added hydrochloric acid (5 ml), followed by stirring at room temperature for 1.5 hours. Then, hydrochloric acid (2.5 ml) was further added thereto, followed by stirring at room temperature for 2 hours. The solvent was evaporated, to give the title compound (1.148 g, crude) as a yellow oil. It was used in the next reaction without carrying out a further purification.

Workup

  1. stirringby stirring at room temperature for 2 hours
  2. customThe solvent was evaporated

Sources & evidence

ORD record
ord-2bdfa41552ae441aa85437998f09b4f0
Source dataset
uspto-grants-2010_11
Patent number
US07834049B2

Reaction notes

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