Hydrochloric Acid → HCID 86639466, compound

HRID 1173770Notes

Reaction equation

HRID 1173770 reaction equation
CC1[O:3][C@H:4]([C:10]([O:12][CH3:13])=[O:11])[C@H:5]([CH2:7][CH2:8][CH3:9])[N:6]=1.[ClH:14]>CO>[ClH:14].[NH2:6][C@@H:5]([CH2:7][CH2:8][CH3:9])[C@H:4]([OH:3])[C:10]([O:12][CH3:13])=[O:11]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 59203392HCID 59203392, compound

Product 1

HCID 86639466HCID 86639466, compoundYield 50%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Methyl (4S,5S)-2-methyl-4-propyl-4,5-dihydro-1,3-oxazole-5-carboxylate (0.2 g, 1.1 mmol), methanol (2 ml) and concentrated hydrochloric acid (0.25 ml) were mixed, and the mixture was stirred at room temperature for 3 hours. The solvent was evaporated away under reduced pressure to obtain the title compound as a white solid (0.1 g, yield: 50%).

Workup

  1. customThe solvent was evaporated away under reduced pressure

Sources & evidence

ORD record
ord-79ca3ea1ea30488dac44a95fe94974b7
Source dataset
uspto-grants-2010_11
Patent number
US07834190B2

Reaction notes

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