反应详情

温度

25 °C

A solution of the product from Example 6A (0.50 g, 1.30 mmol) in THF (13 mL) was treated with the product from Example 5A (0.30 g, 1.59 mmol), DEPBT (0.45 g, 1.50 mmol), and N,N-diisopropylethylamine (1.1 mL, 6.31 mmol), stirred at 25° C. for 16 hours, and partitioned between ethyl acetate and 10% Na2CO3 solution. The organic phase was washed with additional 10% Na2CO3 solution and brine, dried over MgSO4, filtered and concentrated to give the title compound, used without further purification.

1. custompartitioned between ethyl acetate and 10% Na2CO3 solution
2. washThe organic phase was washed with additional 10% Na2CO3 solution and brine
3. dry with materialdried over MgSO4
4. filtrationfiltered
5. concentrationconcentrated