反应详情

温度

50 °C

A solution containing the product from Example 119A (0.095 g, 0.14 mmol) in THF (1 mL) was treated with a solution of HCl in dioxane (0.25 mL, 4 N), stirred at 50° C. for 16 hours, cooled and concentrated under reduced pressure. The residue was dissolved in ethanol and concentrated several times to give the title compound as hydrochloride salt, which was used without further purification.

1. temperaturecooled
2. concentrationconcentrated under reduced pressure
3. dissolutionThe residue was dissolved in ethanol
4. concentrationconcentrated several times