反应详情

A solution of 2-benzyl-5-methyloctahydropyrrolo[3,4-c]pyrrole (2.4 g) in methanol (60 ml) was mixed with ammonium formate (2.1 g) and palladium on carbon (5%, 0.12 g), and the mixture was refluxed for 8 hours. After cooling, the reaction solution was filtered and concentrated. The crude product could be directly reacted further. The product with the molecular weight of 126.20 (C7H14N2); MS (ESI): 127 (M+H+) was obtained in this way.

1. temperaturethe mixture was refluxed for 8 hours
2. temperatureAfter cooling
3. filtrationthe reaction solution was filtered
4. concentrationconcentrated
5. customThe crude product could be directly reacted further
6. customMS (ESI): 127 (M+H+) was obtained in this way