Phenyl isocyanate → HCID 15895594, compound

HRID 1176189Notes

Reaction equation

HRID 1176189 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][OH:7])=[CH:4][CH:3]=1.[N:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[C:11]=[O:12]>ClCCl>[OH:7][CH2:6][C:5]1[CH:8]=[CH:9][C:2]([NH:1][C:11]([NH:10][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:12])=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 693314-Aminobenzyl alcohol

Product 1

HCID 15895594HCID 15895594, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 3.75 g 4-aminobenzylalcohol and 3.3 ml isocyanato-benzene in 120 ml dichloromethane was stirred at 23° C. for 2 hours. Afterwards, the reaction mixture was filtered. The crystalline product was washed with diethylether. 6.82 g product was obtained which was used without further purification.

Workup

  1. filtrationAfterwards, the reaction mixture was filtered
  2. washThe crystalline product was washed with diethylether

Sources & evidence

ORD record
ord-3a098eda71ea48f298c7dad8b749d6ab
Source dataset
uspto-grants-2010_11
Patent number
US07842809B2

Reaction notes

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