Dimethylformamide → N-(3-(isopropylcarbamoyl)phenyl)-4-methyl-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide

HRID 117672Notes

Reaction equation

HRID 117672 reaction equation
[CH3:1][C:2]1([C:18](=[O:19])[OH:20])[CH2:3][CH2:4][N:5]([c:8]2[c:9]3[c:10]([n:11][cH:12][n:13]2)[nH:14][cH:15][c:16]3[CH3:17])[CH2:6][CH2:7]1.[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[NH2:52][c:53]1[cH:54][c:55]([C:56](=[O:57])[NH:58][CH:59]([CH3:60])[CH3:61])[cH:62][cH:63][cH:64]1.[O:65]=[CH:66][N:67]([CH3:68])[CH3:69].[P-:21]([F:22])([F:23])([F:24])([F:25])([F:26])[F:27].[n:28]1([O:29][C:30]([N:31]([CH3:32])[CH3:33])=[N+:34]([CH3:35])[CH3:36])[c:37]2[n:38][cH:39][cH:40][cH:41][c:42]2[n:43][n:44]1>>[CH3:1][C:2]1([C:18](=[O:19])[NH:52][c:53]2[cH:54][c:55]([C:56](=[O:57])[NH:58][CH:59]([CH3:60])[CH3:61])[cH:62][cH:63][cH:64]2)[CH2:3][CH2:4][N:5]([c:8]2[c:9]3[c:10]([n:11][cH:12][n:13]2)[nH:14][cH:15][c:16]3[CH3:17])[CH2:6][CH2:7]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 9886HexafluorophosphateHCID 30190233-amino-N-(isopropyl)benzamideHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 670367814-methyl-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4yl)-piperidine-4-carboxylic acid

Product 1

HCID 44478472N-(3-(isopropylcarbamoyl)phenyl)-4-methyl-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide

Sources & evidence

ORD record
ord-578f6e15c2be46dcb4f918ea1b27e763
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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