m-Chloroperbenzoic acid → HCID 178526236, compound

HRID 1180904Notes

Reaction equation

HRID 1180904 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][CH:9]=[CH:10][C:3]=12.ClC1C=CC=C(C(OO)=[O:19])C=1>C(OCC)C>[Br:1][C:2]1[CH:7]=[CH:6][N+:5]([O-:19])=[C:4]2[NH:8][CH:9]=[CH:10][C:3]=12

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 222736434-Bromo-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 178526236HCID 178526236, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 4-bromo-1H-pyrrolo[2,3-b]pyridine (25 mmol) in diethyl ether (400 mL) under nitrogen at room temperature was added m-chloroperbenzoic acid (40 mmol). The reaction was stirred for 2.5 h. The resultant precipitate was filtered and washed with cold ether (50 mL) to give the title compound as an off-white solid (87%). ESMS[M+H]+: 213.2

Workup

  1. filtrationThe resultant precipitate was filtered
  2. washwashed with cold ether (50 mL)

Sources & evidence

ORD record
ord-83238d034b8c4e38958dcd8fa1046abd
Source dataset
uspto-grants-2007_10
Patent number
US07282588B2

Reaction notes

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