2-Methoxyethylamine → HCID 58981153, compound

HRID 1181721Notes

Reaction equation

HRID 1181721 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH2:11][N:12]1[CH:20]([C:21]2[N:25]([CH3:26])[CH:24]=[C:23]([C:27]([OH:29])=O)[CH:22]=2)[C:19]2[C:18](=[O:30])[NH:17][C:16](=[O:31])[N:15]([CH2:32][CH:33]([CH3:35])[CH3:34])[C:14]=2[N:13]1C.[CH3:37][O:38][CH2:39][CH2:40][NH2:41].[C:42](P(=O)(OCC)OCC)#N>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH2:11][N:12]1[C:20]([C:21]2[N:25]([CH3:26])[CH:24]=[C:23]([C:27]([NH:41][CH2:40][CH2:39][O:38][CH3:37])=[O:29])[CH:22]=2)=[C:19]2[C:14]([N:15]([CH2:32][CH:33]([CH3:34])[CH3:35])[C:16](=[O:31])[N:17]([CH3:42])[C:18]2=[O:30])=[N:13]1

Participants

4

Reactant 3

HCID 80182-MethoxyethylamineHCID 76257Diethyl cyanophosphonateHCID 69430784HCID 69430784, compound

Product 1

HCID 58981153HCID 58981153, compound

Procedure

This compound was synthesized by the reaction of 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-1-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylic acid and 2-methoxyethylamine using diethyl cyanophosphonate as a coupling reagent. Mass: 566.10 (M+H).

Sources & evidence

ORD record
ord-cde3d782ebe040208f1ede8db2440a03
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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