N,N-Dimethylethylenediamine → HCID 58981156, compound

HRID 1181738Notes

Reaction equation

HRID 1181738 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[C:5]2[CH2:12][N:13]1[C:21]([C:22]2[N:26]([CH3:27])[CH:25]=[C:24]([C:28](O)=[O:29])[CH:23]=2)=[C:20]2[C:15]([N:16]([CH2:34][CH:35]([CH3:37])[CH3:36])[C:17](=[O:33])[N:18]([CH3:32])[C:19]2=[O:31])=[N:14]1.[CH3:38][N:39]([CH3:43])[CH2:40][CH2:41][NH2:42].C(P(=O)(OCC)OCC)#N>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[C:5]2[CH2:12][N:13]1[C:21]([C:22]2[N:26]([CH3:27])[CH:25]=[C:24]([C:28]([NH:42][CH2:41][CH2:40][N:39]([CH3:43])[CH3:38])=[O:29])[CH:23]=2)=[C:20]2[C:15]([N:16]([CH2:34][CH:35]([CH3:37])[CH3:36])[C:17](=[O:33])[N:18]([CH3:32])[C:19]2=[O:31])=[N:14]1

Participants

4

Reactant 3

HCID 66053N,N-DimethylethylenediamineHCID 76257Diethyl cyanophosphonateHCID 58981061HCID 58981061, compound

Product 1

HCID 58981156HCID 58981156, compound

Procedure

This compound was synthesized by the reaction of 5-{2-[(6-chloroquinolin-4-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylic acid and N,N-dimethylethane-1,2-diamine using diethyl cyanophosphonate as a coupling reagent. Mass: 591.27 (M+H).

Sources & evidence

ORD record
ord-00a580f28f674380bc7d1ddd80a33e72
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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