HRID1181774

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3939

Lithium hydroxide anhydrous

HLiO

结构：CC(=O)Oc1ccc(Cn2c(=O)n(C)c(=O)c3c(-c4ccncc4)n(Cc4cccc5ccccc45)nc32)cc1

HCID69428081

未命名化合物

PRODUCTS

生成物

结构：Cn1c(=O)c2c(-c3ccncc3)n(Cc3cccc4ccccc34)nc2n(Cc2ccc(O)cc2)c1=O

HCID58980990

未命名化合物

PROCEDURE

实验过程

This compound was synthesized by the hydrolysis of 4-{[5-methyl-2-(1-naphthylmethyl)-4,6-dioxo-3-pyridin-4-yl-2,4,5,6-tetrahydro-7H-pyrazolo[3,4-d]pyrimidin-7-yl]methyl}phenyl acetate with 0.5N LiOH at room temperature for six hours. Mass: 489.80 (M+H).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-84292c1239ec42d7a11a5584b753e944
来源数据集: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07285558B2
来源说明: uspto-grants-2007_10

反应 SMILES

C([O:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][N:12]2[C:17]3=[N:18][N:19]([CH2:27][C:28]4[C:37]5[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=5)[CH:31]=[CH:30][CH:29]=4)[C:20]([C:21]4[CH:26]=[CH:25][N:24]=[CH:23][CH:22]=4)=[C:16]3[C:15](=[O:38])[N:14]([CH3:39])[C:13]2=[O:40])=[CH:7][CH:6]=1)(=O)C.[Li+].[OH-]>>[OH:4][C:5]1[CH:6]=[CH:7][C:8]([CH2:11][N:12]2[C:17]3=[N:18][N:19]([CH2:27][C:28]4[C:37]5[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=5)[CH:31]=[CH:30][CH:29]=4)[C:20]([C:21]4[CH:22]=[CH:23][N:24]=[CH:25][CH:26]=4)=[C:16]3[C:15](=[O:38])[N:14]([CH3:39])[C:13]2=[O:40])=[CH:9][CH:10]=1