Dimethylformamide → 5-[(1H-Indazol-4-ylmethyl)-carbamoyl]-3-trifluoromethyl-thiophene-2-carboxylic acid methyl ester
Reaction equation
[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:14](=[O:15])[OH:16])[cH:8][c:9]1[C:10]([F:11])([F:12])[F:13].[O:69]=[CH:70][N:71]([CH3:72])[CH3:73].[OH:48][n:49]1[c:50]2[c:51]([cH:52][cH:53][cH:54][cH:55]2)[n:56][n:57]1.[P-:24]([F:25])([F:26])([F:27])([F:28])([F:29])[F:30].[n:31]1([O:32][C:33]([N:34]([CH3:35])[CH3:36])=[N+:37]([CH3:38])[CH3:39])[c:40]2[cH:41][cH:42][cH:43][cH:44][c:45]2[n:46][n:47]1.[nH:58]1[n:59][cH:60][c:61]2[c:62]([CH2:67][NH2:68])[cH:63][cH:64][cH:65][c:66]12>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:14](=[O:16])[NH:68][CH2:67][c:62]2[c:61]3[cH:60][n:59][nH:58][c:66]3[cH:65][cH:64][cH:63]2)[cH:8][c:9]1[C:10]([F:11])([F:12])[F:13]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-93b8d9ea23d84aedb4480cbe800468ac
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…