Chloroform → 2-Amino-3,5-difluoro-6-(p-methoxybenzylamino)-4-methylpyridine
Reaction equation
[CH3:19][O:20][c:21]1[cH:22][cH:23][c:24]([CH2:25][NH2:26])[cH:27][cH:28]1.[CH3:1][N:2]1[CH2:3][CH2:4][CH2:5][C:6]1=[O:7].[CH:29]([Cl:30])([Cl:31])[Cl:32].[NH2:8][c:9]1[n:10][c:11]([F:18])[c:12]([F:17])[c:13]([CH3:16])[c:14]1[F:15]>>[NH2:8][c:9]1[n:10][c:11]([NH:26][CH2:25][c:24]2[cH:23][cH:22][c:21]([O:20][CH3:19])[cH:28][cH:27]2)[c:12]([F:17])[c:13]([CH3:16])[c:14]1[F:15]Participants
5
Sources & evidence
- ORD record
- ord-216e57d4327e4a3d98e55cd0a8a037f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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