反应详情

2.24 g (7.4 mmol) of tert-butyl 3-[(5-cyanopyridin-2-yl)amino]piperidine-1-carboxylate (Example 8A) were dissolved in 4.3 ml of a hydrochloric acid solution in dioxane (4 M) and stirred at RT for 3 h. On completion of reaction, the solvent was removed completely. 1.74 g (90% of theory) of the product were obtained in solid form.

1. customOn completion of reaction
2. customthe solvent was removed completely
3. custom1.74 g (90% of theory) of the product were obtained in solid form