Dimethylamine → 5-bromo-N,N-dimethylpicolinamide

HRID 118327Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[OH:10])[n:6][cH:7]1.[CH3:11][NH:12][CH3:13].[CH:14]([N:15]([CH:16]([CH3:17])[CH3:18])[CH2:19][CH3:20])([CH3:21])[CH3:22].[O:47]=[CH:48][N:49]([CH3:50])[CH3:51].[P-:23]([F:24])([F:25])([F:26])([F:27])([F:28])[F:29].[n:30]1([O:31][C:32]([N:33]([CH3:34])[CH3:35])=[N+:36]([CH3:37])[CH3:38])[c:39]2[n:40][cH:41][cH:42][cH:43][c:44]2[n:45][n:46]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:10])[N:12]([CH3:11])[CH3:13])[n:6][cH:7]1

Participants

Reactant 6

HCID 674Dimethylamine

HCID 6228Dimethylformamide

HCID 9886Hexafluorophosphate

HCID 81531Diisopropylethylamine

HCID 6085445-Bromopyridine-2-carboxylic acid

HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

Product 1

HCID 228316185-bromo-N,N-dimethylpicolinamide

Sources & evidence

ORD record: ord-8f6b047f7c154acab12b65d78dcd4331
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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