Methyl Bromide → HCID 131731240, compound
Reaction equation
[CH3:1][Br:2].[CH3:3][N:4]1[CH2:8][CH2:7][CH2:6][C:5]1=[O:9]>>[CH3:1][Br:2].[CH3:3][N:4]1[C:5](=[O:9])[CH2:6][CH2:7][CH2:8]1Participants
3
Conditions
- Temperature
- -10 °C
Procedure
A bottle containing methyl bromide (MeBr; b.p. 4° C.) was cooled down to −10° C. MeBr (50.00 mL) was poured out and weighed (88.53 g; d=1.77 g/mL). The methyl bromide was added into a pre-cooled bottle containing 1-Methyl-2-Pyrrolidinone (NMP) {50.00 mL; 54.39 g, −10° C.} to form approximately 100 mL solution at −10° C. (MeBr/NMP).
Workup
- custom54.39 g, −10° C.
Sources & evidence
- ORD record
- ord-a1f6b643ab8d428388be8f3aa98a4bb0
- Source dataset
- uspto-grants-2014_03
- Patent number
- US08669366B2
Reaction notes
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