反应详情

The coupling of (R)-5-(5-amino-2-fluorophenyl)-6,6-difluoro-5-methyl-2,5,6,7-tetrahydro-1,4-oxazepin-3-amine (intermediate A10A) and 5-ethoxymethyl-pyridine-2-carboxylic acid (which might be prepared in analogy to the isopropyl ether described by Robert M. et al., Int. Patent Application Publ. No. WO2005007658) yielded the title compound as a white solid. MS (ISP): m/z=437.2 [M+H]+.