Tetrahydrofuran → 5-chloro-2-(2-chloro-4-iodo-phenylamino)-N-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-3,4-difluoro-benzamide
Reaction equation
[CH3:33][C:34]1([CH3:42])[O:35][CH2:36][CH:37]([CH2:39][O:40][NH2:41])[O:38]1.[CH:43]([N:44]([CH:45]([CH3:46])[CH3:47])[CH2:48][CH3:49])([CH3:50])[CH3:51].[F:1][c:2]1[c:3]([O:4][C:9]([c:10]2[c:11]([NH:19][c:20]3[c:21]([Cl:27])[cH:22][c:23]([I:26])[cH:24][cH:25]3)[c:12]([F:18])[c:13]([F:17])[c:14]([Cl:16])[cH:15]2)=[O:28])[c:5]([F:6])[c:7]([F:8])[c:29]([F:30])[c:31]1[F:32].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1>>[C:9]([c:10]1[c:11]([NH:19][c:20]2[c:21]([Cl:27])[cH:22][c:23]([I:26])[cH:24][cH:25]2)[c:12]([F:18])[c:13]([F:17])[c:14]([Cl:16])[cH:15]1)(=[O:28])[NH:41][O:40][CH2:39][CH:37]1[CH2:36][O:35][C:34]([CH3:33])([CH3:42])[O:38]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-073e9a166ad6410fb8257221cc799650
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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