Methanol → 2-(5-Chloro-6-(2,2,2-trifluoroethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-3-cyclobutylpropanoic acid
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:38][OH:39].[Cl:1][c:2]1[cH:3][c:4]([CH:24]([C:25](=[O:26])[O:27][CH2:28][CH3:29])[CH2:30][CH:31]2[CH2:32][CH2:33][CH2:34]2)[cH:5][c:6](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13].[Li+:37].[OH-:36].[OH2:35].[OH2:45]>>[Cl:1][c:2]1[cH:3][c:4]([CH:24]([C:25](=[O:26])[OH:27])[CH2:30][CH:31]2[CH2:32][CH2:33][CH2:34]2)[cH:5][c:6](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-7ffbccc05fc143c1b8eda7e1e5520ce0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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